White Coat Waste Takes Aim at Animal Research — From the Right

A conservative political consultant wants to end government funding for research involving animal subjects. Scientists call that a dangerous game.

If there’s any activist who can thrive in Donald Trump’s Washington, it’s Anthony Bellotti, a conservative political consultant who is adept at social media campaigns, at ease with the press, and fluent in the language of small-government politics. Bellotti worked on campaigns to defund Planned Parenthood, the women’s reproductive rights nonprofit, and to end Barack Obama’s signature Affordable Care Act.

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“We’re building a broad left-right coalition for one issue we can all agree on — libertarian, vegetarian.”

But his current effort, called the White Coat Waste Project, has what many might consider an unusual crossover appeal. The group aims to stop government-funded animal research, using a mix of Tea Party-ready rhetoric about government waste and heart-tugging appeals to animal-lovers of all political persuasions. Toward that end, Bellotti makes a straightforward pitch: Animal research, he argues, is cruel, unnecessary, inefficient, and expensive. Plus, much of it is funded by taxpayers, whether they like it or not. The solution, according to White Coat Waste’s website, is to “drain the swamp” and “cut federal spending that hurts animals and Americans.”

“We’re taking an old issue in a new light,” Bellotti told me. “We’re building a broad left-right coalition for one issue we can all agree on — libertarian, vegetarian.”

In the past 12 months, White Coat Waste has focused particular attention on research conducted under the auspices of the Department of Veterans Affairs, shuttering one project in California, triggering internal investigations of a VA lab in Virginia, and helping to get an amendment through the House eliminating funding for VA dog research. (That amendment has not received Senate approval, but Bellotti’s handiwork was enough to provoke a stern response from VA Secretary David Shulkin.) The Food and Drug Administration has also been a Bellotti target, and after more than a year of pressure from White Coat Waste, FDA commissioner Scott Gottlieb shut down an agency research project on nicotine addiction last month, over concerns about its treatment of squirrel monkey subjects.

The federal government spends billions of dollars each year — exact numbers are hard to come by — on research that involves animal subjects, ranging from fruit flies to primates. This research, agencies and scientists say, is essential for making biomedical advances. Shulkin, for example, argued in an op-ed late last year that canine research at the VA was crucial, because of the “distinct physical and biological characteristics humans and dogs share that other species do not.” Such research, he noted, has led directly to developments like the implantable cardiac pacemaker and the artificial pancreas — breakthroughs that “will make real differences in veterans’ lives,” he said.

Indeed, the virtues of animal research — done humanely, and under strict protocols — are so embedded within the scientific and research communities that it would take more than one, small nonprofit to shut that work down.

Still, as White Coat Waste begins to score political victories, it poses serious questions: Can the organization reshape the conversation around animal research? And if so, how far can White Coat Waste go?

Bellotti formed White Coat Waste in 2013, but it wasn’t until 2015 that the organization really started to grow. That year, Bellotti collaborated with the conservative talk show host and commentator Glenn Beck on a short documentary called “Socialized Science.” The organization also received a $100,000 grant from the Greenbaum Foundation, which gives millions of dollars to animal rights causes, and to date, has given nearly $500,000 to White Coat Waste. In 2016, Bellotti hired Justin Goodman, a staffer and lobbyist for the advocacy group People for the Ethical Treatment of Animals, or PETA, as his vice president of advocacy and public policy.

Bellotti explicitly frames White Coat Waste as a taxpayer rights outfit, not an animal rights organization, and he promises never to target private animal research. “It’s about your liberty to be forced to pay for something that you don’t like, don’t want, and don’t need,” Bellotti said.

The approach has pulled in people who might not otherwise show much interest in animal rights issues. Trump advisor Roger Stone, for example, hosted Bellotti on his Infowars show last month. And Pursuit (formerly known as Restore Accountability), a government-spending watchdog group aimed at millennials and founded by Tom Coburn, the former Republican Senator from Oklahoma, partnered with Bellotti on a recent report.

“Good campaigns win — and we’re winning — but great campaigns bring new people into the fight,” Bellotti told me. These are people, he continued, who “are saying, hallelujah, where have you been all my life? I never felt at home with the establishment animal groups.

“Yes, many of those voices are on the Republican side, conservative side, alt-right side,” he added, “but they are saying it.”

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Still, White Coat Waste is not merely gaining support and participation from the right flank, and it has managed to find bipartisan traction in the current Congress. On the VA campaign, Representatives Dave Brat, a Republican from Virginia, and Dina Titus, a Democrat from Nevada, have been two of the organization’s most vocal supporters on the Hill. And the efforts to shut down the VA dog research in California last year were vocally supported by a host of Democrats in Congress, including Nanette Diaz Barragán, Tony Cárdenas, and Alan Lowenthal, among others. In February 2017, White Coat Waste’s leadership formed a political action committee to support candidates in the 2018 election cycle.

This combination of bureaucratic savvy and powerful allies can yield results and, so far, White Coat Waste has been most effective at targeting specific federal research programs, finding problems with their animal care procedures, and then applying public pressure through social media campaigns and high-profile partnerships. In late 2016, for example, White Coat Waste filed a Freedom of Information Act request for documents about the FDA study on nicotine addiction. The researchers were trying to understand how nicotine dosage levels affect the formation and maintenance of addictive behavior. Because scientists cannot ethically use human subjects in such experiments, the researchers proposed to use squirrel monkeys.

Studies on small rodents often pave the way to observations on human subjects. But a conservative activist believes those studies shouldn’t be conducted on the taxpayer’s dime.

Visual: Undark Illustration; Photo via U.S. National Library of Medicine

From the perspective of a taxpayer advocacy organization, the study does not seem like a high priority: It was funded by the FDA’s Center for Tobacco Products, which receives its nine-figure budget from special user fees paid by the tobacco industry. (Asked why his organization targeted non-taxpayer-funded work, Bellotti responds that all FDA research involves taxpayer money in some capacity, and that the user fees are a kind of tax.)

From the perspective of an animal rights organization, though, this study was a natural target. It was basic research, meaning that it may not have immediate utility. It involved squirrel monkeys — tiny, charismatic primates — with catheters implanted in their bodies. And, according to the documents White Coat Waste obtained, four of the monkeys had died after research-related procedures.

The group described the research as “wasteful and cruel” and criticized the FDA for supporting work that “addicts baby monkeys to nicotine.” In September of last year, Bellotti enlisted primatologist Jane Goodall, who wrote a letter to FDA commissioner Scott Gottlieb questioning, among other things, why the FDA needed to learn more about smoking.

In response, a group of 46 tobacco and addiction researchers signed an open letter, published on the website of the animal research advocacy group Speaking of Research, challenging Goodall. The researchers argued that animal research was essential for understanding the biology of addiction, and they accused Goodall and White Coat Waste of misrepresenting the research.

What would happen if the federal government simply stopped doing animal research? “Biomedical progress stops in its tracks,” Buckmaster said.

In the end, though, Gottlieb suspended the study, and in January — after a long process — the FDA permanently shut down the experiment, citing animal welfare concerns. They also announced a third-party investigation into the agency’s oversight of animal research, and the appointment of new Animal Welfare Council to oversee agency procedures.

A spokeswoman for the agency, Tara Rabin, did not answer a list of emailed questions from Undark regarding the decision to shut down the study, and soliciting more details about the welfare councils. But Amanda Dettmer, a senior editor at Speaking of Research and a behavioral neuroscientist who has worked with primates, expressed frustration with the FDA’s decision. “It had the appearance of selectively responding to one party over the other,” she said of Gottlieb’s reaction to Goodall’s letter.

More broadly, Dettmer suggested, the kind of activism that Bellotti and his allies are practicing can seem reckless, if not downright delusional. “The fact of the matter is, we are not yet at a point as a society where we have an alternative,” Dettmer told me. “We’re just not yet at a place where we can make scientific progress or breakthroughs in public health without relying on animal models for certain questions. And so by taking that extremist standpoint — that essentially cuts off scientific progress and potential treatments for the public.”

I asked Alice Ra’anan, director of government relations and science policy at the American Physiological Society, whether she had seen an organization like White Coat Waste during her 25-year career at the APS. She said that bipartisan efforts for animal rights were not new. “What I think is a little different is the explicit rhetoric alleging government spending, and [that] the tactics are more explicitly directed toward members of Congress,” Ra’anan said.

I asked her if that rhetoric seemed to be working. “I think they’re using the kinds of tactics that are being used broadly in our society in political discourse,” she said. “I will leave you to judge how effective these kinds of tactics are.”

Probably the most forceful responses to White Coat Waste have come from Cindy Buckmaster, director of the Center for Comparative Medicine at Baylor College of Medicine and the chair of Americans for Medical Progress, an organization that supports responsible animal research. In our conversation, Buckmaster criticized White Coat Waste’s tactics, which she characterizes as “extremist.” And she expressed frustration that too few people understand the kinds of tradeoffs that push scientists to use animals for their research, all in the pursuit of developing treatments that will save human lives.

What would happen if the federal government simply stopped doing animal research? “It would be catastrophic,” Buckmaster said. “Basically, what happens is biomedical progress stops in its tracks.”

  • “Taxpayers shouldn’t be forced to pay over $15 billion every year for wasteful and cruel experiments on dogs, cats, monkeys and other animals,” the group declares on its website. Critics, however, say it’s not that simple.

For his part, Bellotti considers such claims to be overheated, and he described the FDA’s most recent decision to halt the nicotine experiments as “a complete and total win.” White Coat Waste and its partners, he told me, were feeling “absolute euphoria.”

“Have a Kickstarter, do a bake sale, sell Girl Scout cookies — I don’t care how you do it. Just don’t make me pay for it.”

As he sees it, ending taxpayer-funded animal research would do little to prevent the sort of pioneering, breakthrough-driven research that Buckmaster and others say would come to a halt. Rather, Bellotti argues, the private sector would simply pick up the slack for lifesaving research that requires animal subjects. “If you’re really saving sick kids, then a lot of money can be made from that,” he told me. “Surely someone would want to invest in a miracle cure for sick veterans or sick kids. And they will! There’s pharma, there’s Wall Street, there’s Silicon Valley. Have a Kickstarter, do a bake sale, sell Girl Scout cookies — I don’t care how you do it. Just don’t make me pay for it.”

To be sure, the debate over federal funding for research in general, and about the use of animal models in particular, was roiling long before Bellotti and his allies came onto the scene. Critics of animal research, after all, have long argued that medical researchers rely too heavily on animal models, which often fail to produce results that apply to human beings. And there are robust debates over the current government model of basic research funding. The problem is that Bellotti’s conviction that scientists are burning through billions of dollars on cruel and senseless research is, by almost any fair assessment, a woefully distorted caricature — one that fails to capture both the nuances of these longstanding debates, and the very real ethical challenges that go into making decisions about when animal research is justified.

And yet, the White Coat Waste Project, with its strident calls for government transparency, does shine a bright light on a problem that is inherent to the nation’s multibillion-dollar research funding complex — and it’s an issue on which both Bellotti and Buckmaster would seem to agree: Ordinary citizens have very little voice in determining how their tax dollars are spent in the pursuit of basic science.

“You’ve got to be able to explain what you do,” said Bellotti, issuing a challenge to researchers.

Buckmaster seemed to welcome that conversation.

The public, she said, “are actually the ones demanding [animal research] every time they say they want a cure for this and that. They deserve to know exactly how these cures and treatments come to be.”

Michael Schulson is an American freelance writer covering science, religion, technology, and ethics. His work has been published by Pacific Standard magazine, Aeon, New York magazine, and The Washington Post, among other outlets, and he writes the Matters of Fact and Tracker columns for Undark.

Top visual: World Health Organization via U.S. National Library of Medicine
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12 comments / Join the Discussion

    Companies are for profit yet most of their r&d $$ comes from taxpayers!!! Almost 100% upside and then when the drugs come to market they gouge those who need it. But but they are saving lives. Hahaha yeah.

    Materialism has been proven a failed theory yet they continue to see us as mechanical things. Because drugs have no impact on mind-based and quantum healing modalities; of course just fixing the food supply (and eliminating the chemical assault) will do.


    Science and “advanced (at whatever time introduced) technology” created the health problems we have today.

    And the solution is to mess with and harm another species to prove for-profit drugs will fix the problems that science and technology created.

    Is there a single damn pharma drug that doesn’t harm and cause yet other disorders and the need for yet more drugs?

    These drugs often cause nutritional deficiencies (often WHY they are prescribed in the first place – doctors up to a few years ago received less than two weeks of study in nutrition -DUH, but naturally if why they are writing scripts is mostly related to nutritional deficiencies.

    Refined sugar and modern semi-dwarf wheat variety are what cause almost all modern disease. It’s like this big secret that shouldn’t even exist, but it does. Why?


    How utterly vile to claim this flurry of activity is to “help save lives.” Then stop destroying the food supply with “technology” and “science.”

    Stop advancing for efficiency when the loss comes in nurtitional value to the end user.


    as s small exemplar of public sector vs private sector bio-med research.. years ago NIH ,(ie F Collins) had a monopoly on sequencing the human genome … it was taking years, and $millions. Then along came Craig Venter from the private sector w his new “shotgun sequencing”, which despite the NIH naysayers, did in one year at fraction of the cost what it had taken many years and many million $ for NIH. The competition rather than govt/NIH monopoly was best thing that ever happened to DNA sequencing. NASA is also being forced to lose its space monopoly for same reasons … way too expensive, too little ‘translation”


    The usual ignorant pontificating. Jonah “once saw a picture of a lab animal.” Pippin claims that “much of this entrenched animal research can be replaced with human-relevant methods that are more accurate, faster, and less expensive,” but does not back that up with facts or state his own credentials. Mayor states that “animal tests do not have a very good success rate, irrespective of whether or not it is the result of animal testing,” which is not only contradictory, but lacks a basis in fact as well as a definition of success. It is true that lab animals are not just small, furry humans, which is why it takes years of training and experience to interpret the results correctly. But based on 40+ years in biopharmaceutical research, I can assure you that there is no better model of a living human being than a living animal. What is often ignored in criticizing the “success rate” of drugs in human testing is the fact that thousands of prospective drugs never make it into humans because they are not active or not safe in animals. The success rate would be even worse, or zero, if not for animal research.


    It is hard to believe that in 2018 someone still says that “there is no better model of a living human being than a living animal.” Living animals are horrible models for human beings and everyone (but you, apparently) already knows that. The time for thinking that those who criticises the use of animals in science do not know what they are saying has passed. Everyone is investing in alternatives because it is clear that animal models do not work, let alone the ethical and moral issues implicated. iPSCs, organoids, 3D cultures, bioinformatics, biomarkers…everyone is playing with better ways to understand human diseases and you still think that animals are better. If the money wasted with research using animals were all used to develop even better non-human models we would have by now not just more drugs but drugs that are affordable. Some papers for you to check to be up-to-date:
    Pound P, Bracken MB. Is animal research sufficiently evidence based to be a cornerstone of biomedical research? BMJ 2014;348:g3387–g3387.
    Scannell JW, Blanckley A, Boldon H, Warrington B. Diagnosing the decline in pharmaceutical R&D efficiency. Nat Rev Drug Discov 2012;11:191–200.
    Clerc P, Lipnick S, Willett C. A look into the future of ALS research. Drug Discov Today 2016;21:939–49.
    Langley GR. Considering a new paradigm for Alzheimer’s disease research. Drug Discov Today 2014;19:1114–24.
    Muotri AR. The Human Model: Changing Focus on Autism Research. Biol Psychiatry 2016;79:642–9.
    UK I. A non-animal technologies roadmap for the UK Advancing predictive biology 2015:1–20.

    Please, let the progress move on. Let it go the animals. Say hello to a brighter future.


    “If you’re really saving sick kids, then a lot of money can be made from that,” he told me. “Surely someone would want to invest in a miracle cure for sick veterans or sick kids.”

    This statement by Bellotti is independent on how you achieve such a miracle cure. So, why doesn’t Bellotti oppose human based research as well? As he should know, a very large part of the NIH budget is to do human-based clinical research. Surely, one expects him to argue, the private sector could take care of that as well.

    The fact that he does not seem to oppose such work means only one thing — He is just an animal right fanatic trying to fool people into his position by passing as someone he is not.


    I once saw a picture of a lab animal so covered in tumors and lesions I could not identify the species. I was thoroughly horrified.

    Vivisection is barbaric and morally disgusting. It has no place in a civilized society.


    Not touched on here is the jaw-dropping futility of animal research regarding human diseases. For example, NIH has confirmed that at least 95% of drug research using animals leads to failed clinical trials…costing billions and leaving the public with nothing. The same story can be told for the major disorders that frighten and shorten the lives of Americans…Alzheimer disease, stroke, multiple sclerosis, cancers, etc. Add to this the fact that much of this entrenched animal research can be replaced with human-relevant methods that are more accurate, faster, and less expensive than using animals who cannot replicate human diseases. But animal research is an industry where careers and profits are underwritten by taxpayers and guaranteed by other researchers who sit on the committees that make funding decisions. It’s a racket, a house of cards, a self-perpetuating boondoggle.


    I was curious about the source of JP’s statement ”The NIH has confirmed that at least 95% of drug research using animals leads to failed clinical trials.” Based on some research, I learned that it comes from this document: http://bit.ly/2oIWvjM. It’s not a peer-reviewed research paper. Nor is it an NIH statement on the use of animals. Instead, it’s an online request from one of the 27 NIH institutes. Back in 2015, they were looking for input on their strategic plan. This document was their request for input.

    But that isn’t the biggest issue. The real problem is that the document is not specifically about animal studies. In fact, a search reveals it does not even include the word “animal.”

    Here’s the key sentence for JP’s claim:

    “Currently, a novel intervention can take about 14 years and $2 billion to develop, with a failure rate exceeding 95 percent.”

    So…assuming that this document, which is by no means a major NIH document, is correct, the success rate would be 5 percent.


    Proven: The development of drugs and treatments is a huge, incredibly complex process.

    Also proven: Animals are part of the process in the development of interventions.

    Not proven: That animals are “to blame” for the 5 percent rate (again…assuming it is accurate in the first place.)

    Of course, the overall success rate would be tied to a lot of things including: study design, genetics data, safety testing, the population that was involved in each phase of the clinical trial, animal data, and a bunch of other factors.

    Of course…the most likely conclusion is that the final success rate is the result of dozens if not hundreds of factors.

    One major problem with this longstanding debate? When statistics like that one are characterized as “proof.”


    Actually, I don’t believe that Pippin claimed this as proof that animal testing results in 95% “failure.” What it does INDICATE is that animal tests do not have a very good success rate, irrespective of whether or not it is the result of animal testing.


    Jim Newman..if it comes from an article authored by FS Collins, the director of NIH, will you believe in the 95% failure rate?

    Here it goes “The medical benefits of the current revolution in biology clearly cannot be achieved without vigorous and effective translation. Yet the triple frustrations of long timelines, steep costs, and high failure rates bedevil the translational pathway. The average length of time from target discovery to approval of a new drug currently averages ~13 years, the failure rate exceeds 95%, and the cost per successful drug exceeds $1 billion, after adjusting for all of the failures (1, 2). In this Commentary, I describe the goals, functions, and structure of the National Center for Advancing Translational Sciences (NCATS), a new entity currently being shaped by the U.S. National Institutes of Health (NIH) to reengineer the process of developing diagnostics, devices, and therapeutics.”

    Plus this “The use of small and large animals to predict safety in humans is a long-standing but not always reliable practice in translational science (22). New cell-based approaches have the potential to improve drug safety prediction before use in patients (23). The NIH-EPA-FDA Tox21 consortium has already begun this effort (24), which may benefit from the use of (i) three-dimensional tissue-engineered organoids representative of human heart, liver, and kidney and (ii) induced pluripotent stem cells derived from individuals of selected genotypes that may allow an in vitro assessment of pharmacogenomics (25).”

    Plus this: “The use of animal models for therapeutic development and target validation is time consuming, costly, and may not accurately predict efficacy in humans (28, 29). As a result, many clinical compounds are carried forward only to fail in phase II or III trials; many others are probably abandoned because of the shortcomings of the model. Building on a potentially extensive network of collaborations with academic centers and advocacy groups, NCATS will aim to develop more reliable efficacy models that are based on access to biobanks of human tissues, use of human embryonic stem cell and induced pluripotent stem cell models of disease, and improved validation of assays. ”

    Reference here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101940/



    It is naive to assume that the free market will spend significant amounts of money in areas with little change for monetary return. Pharmaceutical companies are just that, companies, not non-profits.

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